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Black Tie Health and Wellness 1 2

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Black Tie International Magazine:Wellness - Sierra Sciences


Sierra Sciences Graphic

"The Good Life at 125"

 Extending our healthspans and lifespans
beyond the theoretical maximum of 125 years.



The film is finally available on VOD platforms. Yippie! At the time of this email, The Immortalists is #1 on "Notable Indies" on iTunes. That's pretty cool! It's also available in the following places if you would like to share the film with your friends on social media. Please share these links and help us get the word out there about the film! (These are U.S. links only for now)

Google Play:

Bill Andrews

Bill Andrews, Ph.D.
President and CEO


Sierra Sciences, LLC is a company devoted to finding ways
to extend our healthspans
 and lifespans beyond the theoretical maximum of 125 years.


Scientific research has shown that this theoretical maximum is limited because of the length of our telomeres which shorten as we get older. Our reproductive cells don’t experience this shortening, and thus don’t age, because they contain an enzyme called telomerase that re-lengthens the telomeres as they shorten. Sierra Sciences is searching for pharmaceuticals that will induce the production of telomerase in all our cells.

On November 6th, 2007 Sierra Sciences found its first telomerase inducing chemical; called Sierra1. This chemical is the first ever discovered that activates the telomerase gene without killing the cells. Efforts are presently underway to learn everything possible about Sierra1. But, in addition, Sierra1 has provided Sierra Sciences with the first positive control ever for detection of telomerase gene activity in normal human cells. This has served as a very powerful tool for the development of robust high throughput screening assays for finding additional telomerase inducing chemicals. As such, in the last year Sierra Sciences has discovered an additional 62 chemicals that activate the telomerase gene. This now enables the scientists at Sierra Sciences to design better chemicals with increased potency and specificity. Additional screening for even more chemicals is also underway.


Research at Sierra Sciences

§        10,200 Square Foot Facility and Expanding.


§        95% Science, 5% Business


§        30 Scientists, 5 non-Scientists and Growing.


§        Located in Reno, Nevada


Our Progress:

The Search for Telomerase Inducers

We have screened 58,000 Compounds

We have found 109 telomerase inducers

These represent 26 distinct drug families

Most potent compound = 6% of goal

Check back frequently for updates!

We are screening
 4,000 compounds per week.

Bill Andrews, Ph.D.
President and CEO

Bill Andrews has worked in the biotech industry for 28 years, focusing the last 15 years on finding ways to extend human lifespan through the intervention of telomere shortening in human cells.

Dr. Andrews earned his Ph.D. in Molecular and Population Genetics at the University of Georgia in 1981. He was a Senior Scientist at Armos Corporation and Codon Corporation, Director of Molecular Biology at Codon and at Geron Corporation, and Director of Technology Development at EOS Biosciences.

While Director of Molecular Biology at Geron Corporation, Dr. Andrews was one of the principal discoverers of both the RNA and protein components of human telomerase and was awarded 2nd place as "National Inventor of the Year" in 1997 for this work. He is presently a named inventor on 35 US issued telomerase patents.

Terry McAfee
Vice President of Finance

Terry McAfee leads the finance and administrative functions of Sierra Sciences. He is responsible for financial and government reporting, financial planning and budgeting, and human resources. Mr. McAfee is a financial and business planning professional who has held financial leadership roles with Porsche Cars North America, Bank of America and Swift Newspapers. He has also advised a diverse array of clients in manufacturing, e-commerce and services. Mr. McAfee is a Nevada Certified Public Accountant and an active board member of the Reno Chapter of the Institute of Management Accountants.

Laura Briggs, Ph.D.
Vice President of Research and Discovery

Laura Briggs received her B.S. degree in Nutrition in 1993 and her Ph.D. in Environmental Science and Health in 2000 from the University of Nevada, Reno. After a one-year post-doctoral position at UNR she joined Sierra Sciences in 2001 and is the Director of Cell Biology. Dr. Briggs is also currently serving as the biology Lab Coordinator for Truckee Meadows Community College (TMCC) and has collaborated on research projects at the V.A. Medical Center in Reno, Nevada.


Richard Offerdahl
Chairman of the Board & COO

Richard Offerdahl was granted a BSEE in 1965. Until 1981, he worked in the computer industry. In 1981, he co-founded Zycad Corporation serving as its President until 1986. Zycad's 1984 IPO raised $30 million. While he was President of Zycad, sales rose to $25 million per year. In 1987, he purchased majority interest in Digi International (DGII), a maker of computer serial cards and ports for connecting peripherals to networks, and became its first outside Director. While Mr. Offerdahl was associated with DGII, sales rose from $3 million to $160 million per year. He is also a Director of several private companies.

Pierluigi Zappacosta
Vice President of Business Development

Pierluigi Zappacosta was granted an MS in Computer Science from Stanford in 1978. In 1981, he co-founded Logitech, the leading maker of mice and other personal interface products that enable people to work, play and communicate in the digital world and over a period of 17 years filled various roles including President & CEO. He was instrumental in taking the company public in Switzerland in 1988 and on NASDAQ in 1997, raising a total of $60 million. By the time Mr. Zappacosta left in 1998, sales of Logitech had risen to over $400 million per year. He is also a Director of a number of private companies.


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